Introduction :
Dextrose Anhydrous is produced by re-dissolving Dextrose Monohydrate, refining, evaporation and re-crystallization by seed crystals at elevated temperature.
It is separated by centrifugation, washing and drying. M/S.UNIVERSAL STARCH CHEM ALLIED LTD., manufactures Dextrose Anhydrous-IP.
Application :
Pharmaceutical : Dextrose Anhydrous is formulated with vitamins and Minerals and sold in packets or containers or used during convalescent periods of physical stress by patients, athletes and students. In medical formulations Dextrose is used in tableting (salt tablets) and as a raw material in the fermentation industry for bio-chemical synthesis of antibiotics (penicillin, streptomycin etc.) and vitamin C. via Sorbitol.
Fermentation industry : Dextrose serves as a raw material in the manufacture of citric acid, amino acids, enzymes, lactic acid and ethanol.
Chemical processes : Sorbitol and mannitol methyglucoside, gluconic acid, gluconates also are produced from various chemical reactions with Dextrose Monohydrate.
Dextrose Intravenous Injections:
Specification :
Determination |
I.P. LIMITS |
Results |
Description |
A white crystalline powder. |
Complies |
Identification |
When heated it melts, swells up & burns & an odor of burnt sugar is perceptible. |
Complies |
Appearance and odour of Solution |
Dissolve 10.0g in 15 ml of water. The solution is clear. not more intensely coloured than reference solution BYS7,and is odourless. |
Complies |
Acidity or alkalinity |
NMT 0.15 ml of 0.1 M NaOH per 6 gm of the substance. |
0.095 |
Specific Optical Rotation (10% W/V solution) |
52.50 / -53.30 |
+52.89 |
Arsenic |
NMT 1 ppm |
Complies |
Heavy metals |
NMT 5 ppm |
Complies |
Chloride |
NMT 125 ppm. |
Complies |
Sulphate |
NMT 200 ppm . |
Complies |
Sulphite |
Conforms |
Complies |
Barium |
Conforms |
Complies |
Foreign sugars, soluble starch and dextrins |
Conforms |
Complies |
Sulphated ash |
NMT 0.10 |
0.038 |
Water |
NMT 1.0 % w/w |
0.40 |